Quinolines and derivatives
- (1)
- (1)
- (1)
- (219)
- (6)
- (40)
- (2)
- (12)
- (47)
- (1)
- (37)
- (1)
- (2)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (7)
- (132)
- (1)
- (9)
- (16)
- (1)
- (35)
- (1)
- (1)
- (1)
- (1)
- (1)
- (189)
- (1)
- (1)
- (15)
- (1)
- (17)
- (17)
- (7)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (7)
- (22)
- (26)
- (30)
- (4)
- (6)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (5)
- (2)
- (6)
- (5)
- (2)
- (1)
- (11)
- (1)
- (2)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (25)
- (16)
- (2)
- (3)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (4)
- (4)
- (8)
- (2)
- (1)
- (2)
- (1)
- (1)
- (6)
- (2)
- (1)
- (1)
- (2)
- (1)
- (6)
- (1)
- (20)
- (1)
- (5)
- (1)
- (3)
- (5)
- (1)
- (2)
- (2)
- (2)
- (2)
- (8)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (4)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (5)
- (1)
- (2)
- (5)
- (2)
- (4)
- (2)
- (3)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (4)
- (1)
- (1)
- (3)
- (3)
- (1)
- (7)
- (2)
- (1)
- (4)
- (1)
- (1)
- (1)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (2)
- (3)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (3)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (13)
- (1)
- (2)
- (2)
- (4)
- (3)
- (4)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (19)
- (2)
- (1)
- (2)
- (4)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (4)
- (5)
- (1)
- (2)
- (1)
- (1)
- (2)
- (4)
- (3)
- (2)
- (1)
- (9)
- (2)
- (3)
- (3)
- (2)
- (5)
- (3)
- (13)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (3)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (4)
- (5)
- (4)
- (3)
- (3)
- (7)
- (1)
- (2)
- (3)
- (7)
- (5)
- (2)
- (1)
- (10)
- (1)
- (1)
- (1)
- (2)
- (2)
- (4)
- (1)
- (2)
- (2)
- (4)
- (2)
- (2)
- (6)
- (2)
- (7)
- (4)
- (3)
- (2)
- (2)
- (5)
- (2)
- (1)
- (14)
- (1)
- (1)
- (23)
- (42)
- (24)
- (18)
- (83)
- (3)
- (17)
- (3)
- (5)
- (8)
- (1)
- (6)
- (1)
- (5)
- (1)
- (6)
- (5)
- (2)
- (5)
- (2)
- (6)
- (2)
- (2)
- (4)
- (1)
- (26)
- (19)
- (70)
- (110)
- (3)
- (1)
- (2)
- (59)
- (5)
- (1)
- (1)
- (2)
- (299)
- (2)
- (2)
- (4)
- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (3)
- (9)
- (3)
- (2)
- (62)
- (2)
- (29)
- (3)
- (1)
- (1)
- (3)
- (3)
- (2)
- (1)
- (2)
- (1)
- (5)
- (4)
- (2)
- (1)
- (3)
- (1)
- (2)
- (2)
- (5)
- (3)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (12)
- (4)
- (1)
- (5)
- (3)
- (5)
- (2)
- (2)
- (3)
- (2)
- (1)
- (1)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
Filtered Search Results
Apexbio Technology LLC Zotarolimus(ABT-578) 221877-54-9 25mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Zotarolimus ABT-578 is a small-molecule inhibitor targeting the immunophilin FKBP12 It is designed to form a complex with FKBP12 thereby inhibiting mTOR pathway signaling and suppressing the proliferation of T-cells vascular smooth muscle cells (VSMCs) and endothelial cells (ECs) Zotarolimus ABT-578 exerts its biological activity primarily through mTOR pathway inhibition In cell-based studies zotarolimus demonstrates nanomolar-level inhibitory potency against human coronary artery cell proliferation and T-cell activation Based on these pharmacological properties zotarolimus ABT-578 holds research potential in vascular restenosis prevention neointimal hyperplasia reduction and immunological studies involving T-cell function
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Chemscene CHEMSCENE
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000580069 RESIQUIMOD 250MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Cambridge Isotope Laboratories 1 2 3 8-TetraCN (PCN-31) (unlabeled) 100 ug/mL in nonane 1 mL
1 2 3 8-TetraCN (PCN-31) (unlabeled) 100 ug/mL in nonane 1 mL
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 4-HYDROXYCYCLOHEXAN-1-ONE 10G
5000224201 4-HYDROXYCYCLOHEXAN-1-ONE 10G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
TARGETMOL CHEMICALS INC Gabapentin hydrochloride 200MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Also available in 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Gabapentin hydrochloride (Neurontin HCl) is a GABA analogue, used to treat seizures and neuropathic pain. Purity 99.46%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Lobeglitazone sulfate | 763108-62-9 | 99.6% | 578.61 | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Lobeglitazone sulfate is a novel thiazolidinedione and an orally active agonist for PPAR with EC50 values of 137.4 nM for PPARγ and 546.3 nM for PPARα. It acts as an inhibitor for the ERK/JNK/Smad/NF-κB signaling pathway.
- Exhibits anti-inflammatory, anti-diabetic, anti-fibrotic, and anti-atherosclerotic properties.
- Increases glucose uptake in 3T3-L1 adipocytes and L6 muscle cells.
- Inhibits NO generation and pro-inflammatory cytokines in LPS-stimulated BMDMs.
- Inhibits TGF-β1-induced expression of α-SMA and fibronectin, showing anti-fibrotic properties.
- Inhibits PDGF-induced proliferation and migration of vascular smooth muscle cells.
- Demonstrates anti-atherosclerotic property in ApoE-/- mouse aortic atherosclerosis models.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC Ranolazine 95635-55-5 200mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Ranolazine (CAS 95635-55-5) is a small molecule that acts as an anti-ischemic agent by selectively inhibiting the late sodium current (INaL) in cardiac cells thereby reducing intracellular sodium accumulation and subsequent calcium overload via the Na /Ca2 exchanger This action mitigates adverse effects associated with ischemia-induced ionic imbalance Ranolazine has also been shown to shift ATP production from fatty acid oxidation toward glucose oxidation reflecting greater metabolic efficiency as glucose oxidation yields more ATP per mole of oxygen consumed Additionally it decreases oxygen consumption and suppresses fatty acid-driven ketogenesis in hepatic cells Ranolazine is widely utilized in research focused on myocardial energy metabolism and ischemic heart disease
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Cytochrome c (bovine heart) | 9007-43-6 | MFCD00130890 | 95.0% | 12,327 Da | 200MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Cytochrome c (bovine heart) is a heme-containing mitochondrial protein provided as a lyophilized powder for research use. It functions in electron transport and is commonly used as a reagent or standard in biochemical assays of oxidative phosphorylation, electron-transfer reactions, and apoptosis research. The material is characterized by its protein sequence and heme prosthetic group and is supplied at ~95% purity.
- Heme-containing mitochondrial protein suitable for biochemical studies.
- Commonly used as a reagent or standard in electron transport and apoptosis assays.
- Provided as a lyophilized powder for convenient storage and handling.
- Purity approximately 95.0% as listed by the manufacturer.
- Available in multiple pack sizes, including a 200 mg pack.
- Identified by CAS number 9007-43-6 for reference and traceability.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC EGFR-IN-86 | 3055550-22-3 | 99.9% | 423.49 | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
EGFR-IN-86 is an epidermal growth factor receptor (EGFR) inhibitor, characterized by its high activity against glioblastoma with an IC50 of 1.5 nM. This compound has demonstrated the ability to induce apoptosis and arrest the U87 cell cycle in the G2/M phase, indicating its potential as an anti-glioma agent.
- Acts as an EGFR inhibitor with high potency.
- Exhibits significant activity against glioblastoma.
- Induces apoptosis in cells.
- Arrests the U87 cell cycle in the G2/M phase.
- Available in solid form, with a white to off-white appearance.
- Purity of 99.92% ensures high quality for research applications.
- Easily soluble in DMSO for in vitro studies.
- Can be prepared for in vivo experiments using specific solvent protocols to ensure reliable results.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC PI3K-IN-31 | 1359956-12-9 | 99.3% | 435.43 g/mol | C19H23F2N7O3 | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
PI3K-IN-31 is a small-molecule PI3K inhibitor for research use, showing potent activity across class I PI3K isoforms and reported anticancer effects. Supplied as a high-purity solid or as a DMSO solution, it is intended for preclinical and signaling studies in oncology research.
- Potent multi-isoform PI3K inhibition: PI3Kα 3.7 nM; PI3Kβ 74 nM; PI3Kγ 14.6 nM; PI3Kδ 9.9 nM.
- High purity: 99.33%.
- Available formats: solid (5, 10, 25, 50, 100 mg) and 10 mM solution in DMSO.
- C hemical formula C19H23F2N7O3; molecular weight 435.43 g/mol.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000427282 CINCHONIDINE 50G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC PF-2545920 1292799-56-4 200mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
PF-2545920 is a small-molecule inhibitor targeting phosphodiesterase 10A (PDE10A) It is designed to selectively inhibit PDE10A thereby modulating neuronal cAMP and cGMP signaling within cortico-striato-thalamic circuits PF-2545920 exerts its biological activity primarily through selective inhibition of PDE10A In in vitro studies PF-2545920 demonstrates potent inhibitory activity with an IC50 value of 0 37 nM In experimental mouse models it increases striatal cGMP levels at doses around 1 mg/kg Based on these pharmacological properties PF-2545920 holds research potential in the investigation of PDE10A-associated neurobiology and neuropsychiatric conditions such as schizophrenia
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
TARGETMOL CHEMICALS INC Oxypurinol 200MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Oxypurinol is a xanthine oxidase inhibitor. Oxipurinol is potentially used for the treatment of congestive heart failure. Purity 100%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
TARGETMOL CHEMICALS INC Dexmedetomidine 200MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Also available in 1 mL, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Dexmedetomidine is a Central alpha-2 Adrenergic Agonist. The mechanism of action of dexmedetomidine is as an Adrenergic alpha2-Agonist. The physiologic effect of dexmedetomidine is by means of General Anesthesia. Purity 99.96%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 4-4 6-DIMETHOXY-1 3 5-TR 100G
5000225212 4-4 6-DIMETHOXY-1 3 5-TR 100G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More